Our study aims to understand the different types of cells in the human brain and how they work together.
Objective
By carefully looking at individual brain cells, we can learn about their unique features and where they are located in different parts of the brain. This will help us understand how the brain functions normally and how diseases might change it.
Methods
We will collect brain samples from a diverse group of donors, focusing on healthy brains. Using advanced technology, we will study these cells at a very detailed level, looking at their genes and how they are organized.
Desired Outcomes
This will allow us to build a map of the brain’s cells, which scientists can use to explore how certain diseases, like Alzheimer’s or mental health disorders, develop. The ultimate goal of the study is to create a detailed atlas of brain cells that can help researchers discover new treatments for brain diseases. By making this information available to the public, we hope it will lead to new insights and better treatments for conditions that affect millions of people.
“BICAN is one of three NIH BRAIN Initiative transformative projects outlined in The BRAIN Initiative® 2.0: From Cells to Circuits, Toward Cures report. Together with the BRAIN Initiative Connectivity Across Scales (BRAIN CONNECTS) Network and the Armamentarium for Precision Brain Cell Access, these large-scale projects promise to transform neuroscience research, illuminating foundational principles governing the circuit basis of behavior and informing new approaches to the treatment of human brain disorders.”
Check out more information about The BRAIN Initiative on the National Institute of Health or Nature Portfolio website.